CALARCO LAB, UNIVERSITY OF TORONTO
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Most of our research lies at the intersection of RNA biology and neurobiology. We use a combination of genetics, genomics, computational, and biochemical approaches to answer questions in these two areas of research.
Alternative splicing regulation: using
C. elegans
as a pioneering organism
A localization map of RNA binding proteins at single neuron resolution
Investigating the evolution and functional consequences of tissue-regulated splice variants
Probing RNA binding protein mutants for genetic interactions and behavioural phenotypes
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